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5-in-1 Synergistic Anti-Aging Formula · 60 Enteric-Coated Capsules · 30-Day Supply
Formulated with high-purity NR, L-Ergothioneine (EGT), PQQ, Pterostilbene, and Spermidine to directly boost NAD+ levels, enhance mitochondrial health, and activate cellular renewal.
As a dietary supplement, adults take two (2) capsules daily with water, preferably with a meal, or as directed by your healthcare professional. The advanced enteric-coated capsule design ensures the active ingredients survive stomach acid for maximum bioavailability and absorption in the gut. For optimal results, maintain consistent daily intake.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Always consult with a healthcare professional before starting any new supplement regimen, especially if you are pregnant, nursing, taking medications, or have pre-existing health conditions. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.
AIDEVI NAD+ SUSTAIN is a revolutionary, multi-targeted cellular longevity supplement designed to address the core mechanisms of aging. At its foundation is a highly efficient NAD+ precursor, Nicotinamide Riboside (NR), which directly replenishes declining NAD+ levels to restore cellular energy and vitality.
Unlike single-ingredient NAD+ boosters, NAD+ SUSTAIN features a comprehensive 5-in-1 synergistic formula. It combines NR with four other scientifically backed compounds: L-Ergothioneine (EGT), Pyrroloquinoline Quinone (PQQ), Pterostilbene, and Spermidine. Together, these ingredients not only boost NAD+ but also protect mitochondria from oxidative stress, stimulate the growth of new mitochondria, and activate cellular autophagy—the body's natural cleanup process.
Manufactured in a cGMP-certified facility in the United States, AIDEVI NAD+ SUSTAIN utilizes advanced enteric-coated capsules. This ensures that the delicate active ingredients survive the harsh acidic environment of the stomach and are optimally absorbed in the small intestine, maximizing bioavailability and efficacy.
As we age, our cells face a relentless barrage of stressors, leading to a decline in function, energy, and overall vitality. At the heart of this cellular aging process is the depletion of Nicotinamide Adenine Dinucleotide (NAD+), a crucial coenzyme involved in hundreds of metabolic reactions, including energy production, DNA repair, and gene expression. Research indicates that NAD+ levels naturally decline by approximately 50% between the ages of 40 and 60.
This decline is not merely a passive consequence of aging—it actively drives it. When NAD+ falls, mitochondria become less efficient, and the sirtuin proteins that regulate cellular stress responses become less active. Furthermore, the efficiency of autophagy decreases, leading to the accumulation of dysfunctional organelles.
A landmark first-in-humans clinical trial published in Nature npj Aging demonstrated that supplementing with a combination of Nicotinamide Riboside (NR) and Pterostilbene safely and sustainably increased NAD+ levels in healthy older adults by up to 90%, providing a scientifically validated strategy to combat these core aging mechanisms.
The true power of AIDEVI NAD+ SUSTAIN lies in the synergistic interaction of its five key ingredients. While NR provides the fuel, the co-ingredients ensure that the cellular machinery is protected, repaired, and optimized.
The synergistic interaction of NAD+ augmentation, mitochondrial optimization, and enhanced autophagy creates a powerful axis for cellular rejuvenation. The following benefits are supported by scientific research on our active ingredients.
| Benefit Area | Mechanism | Supporting Evidence |
|---|---|---|
| NAD+ Boost & DNA Repair | NR efficiently replenishes NAD+ levels, fueling energy metabolism and providing the essential substrate for sirtuin-mediated DNA repair. | Dellinger et al., 2017 (Nature) |
| Mitochondrial Health | PQQ stimulates the growth of new mitochondria, while EGT protects existing mitochondria from oxidative damage, maximizing energy output. | Chowanadisai et al., 2010 (PMC) |
| Cellular Cleanup (Autophagy) | Spermidine induces autophagy, clearing out toxic cellular debris and dysfunctional organelles to promote cellular renewal. | Madeo et al., 2018 (PMC) |
| Cognitive & Brain Health | Elevated NAD+ and potent antioxidants (Pterostilbene, EGT) provide neuroprotection against oxidative stress and support mental clarity. | Tian et al., 2023 (PMC) |
| Anti-Aging & Longevity | The synergistic activation of sirtuins (via NR and Pterostilbene) and autophagy pathways supports healthy aging at the genetic level. | Sharma et al., 2023 (Nutrients) |
* These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
AIDEVI NAD+ SUSTAIN is formulated for health-conscious adults seeking a comprehensive, multi-pathway approach to cellular longevity and sustained energy.
As NAD+ levels naturally drop by up to 50% in middle age, supplementing with NR helps restore the cellular energy needed to combat persistent fatigue and maintain an active lifestyle.
The brain requires immense amounts of energy. By supporting mitochondrial function and providing neuroprotective antioxidants, this formula helps maintain focus and mental sharpness.
Hormonal transitions can accelerate cellular stress. NAD+ boosters and autophagy inducers provide critical support during this time. Learn more about anti-aging strategies for women over 40 on our blog.
For those already familiar with the science of aging, this 5-in-1 formula offers a convenient, synergistic stack that targets NAD+ depletion, mitochondrial dysfunction, and impaired autophagy simultaneously.
AIDEVI was crowned "Nutraceutical Brand of the Year" at the Corporate LiveWire Global Awards 2025/26. We maintain uncompromising standards to ensure the safety, purity, and efficacy of every bottle.
